Waters Micromass Q-Tof Premier Mass Spectrometer

Waters Q-Tof Premier Mass Spectrometer is the next generation exact mass API/MALDI MS/MS platform for the Pharmaceutical, Biotechnology and Life Science industries. The Q-Tof Premier Mass Spectrometer, featuring T-Wave (Travelling Wave) technology, offers significant enhancements in mass measurement accuracy, dynamic range (pDRE), sensitivity (Enhanced Duty Cycle) and speed. If you want to quantify, identify, and characterize compounds from simple or complex mixtures, Waters Q-Tof Premier offers the finest blend of innovative analytical capabilities for results you’ll have the ultimate confidence in.

Waters Q-Tof Premier mass spectrometer is the first compact exact mass LC/MS/MS platform to incorporate ACQUITY Ultra Performance LC technology. The ACQUITY UPLC system marks an unparalleled breakthrough in separations science, with innovative technologies that enable significant improvements in performance for your application. So, if you need to characterize mixtures with the ultimate in resolution, sensitivity and speed or require a simple, easy-to-use, direct nanoflow solution (nanoACQUITY UPLC) with unparalleled retention time reproducibility, look no further than Ultra Performance Q-Tof LC/MS/MS.

The Q-Tof Premier is a hybrid orthogonal acceleration Time-of-Flight (oa-ToF) mass spectrometer that enables automated exact mass measurement of precursor and fragment ions to yield the highest confidence in structural elucidation and databank search results.

The Q-Tof Premier is a high-performance platform for MS and MS/MS analyses incorporating:

High sensitivity— High transmission efficiency of ZSpray source technology, T-Wave ion optics, T-Wave collision cell and oa-Tof transmission result in high sensitivity
High resolution— Up to 17,500 FWHM with W-Optics
High mass measurement capability— Routine exact mass measurement (3 ppm RMS) in MS and MS/MS with LockSpray and NanoLockSpray
Enhanced speed— Faster TDC (4 GHZ) delivers acquisition speeds of up to 20 spectra per second—compatible with UPLC-based separations
Dynamic Range Enhancement (pDRE)— Equipped with programmable DRE function, which enables quantitation and exact mass measurement over 4 orders of magnitude
Enhanced Duty Cycle— Enables enhanced sensitivity over targeted m/z ranges for detection of modified components (e.g. in Precursor Ion Discovery)
MALDI— Exchangeable vacuum MALDI source enabling large scale MALDI MS and MS/MS analyses—compatible with 96- and 384-spot target plates
Resolving quadrupole— 4, 8 and 32k Da options
m/z range— up to 100,000 in V-Optics
Intelligent, automated MS/MS acquisition— Data Directed Analysis (DDA) and Precursor Ion Discovery
Source options— LockSpray, NanoLockSpray, IonSABRE, APCI, ESCi and APPI
Ergonomics— New industrial design, reduced instrument footprint